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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb9a0092fe5a0b4aadd91633ff71a567b3b54c447935a21c1e1003e0c3125a80' 
  AND token = 'ykAXve/DfONRlIzjiFTNHXaimMSczpptplz8vNbUyxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}