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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59279fe434650b6f4a3e7b49616572d1dee6e44ef19b482910de3994328f01b1' 
  AND token = 'ZM8rJ5Wo2u/27feiE7QBGHP4AIcl0UMJ0nOb6ehwyBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}