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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0759d4c95c5e680e36182fbeec2b0476c081778de761c2e0b60676bef15b1e' 
  AND token = 'u6Hr3y46u23CXCj2frtQDorvEhWt3ltItMrzzzxW+ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}