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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85114cbfbf3a981dc06e5604262c3c32b47873f0d6e77799bfbeb88294a6b755' 
  AND token = 'X30Xv6XoqASoUuEF0A0/bwwnEXxY4hb9iAU0VhhDjH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}