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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '933cb0197cc1f72117a46b22d6ad98378991b176d72b7c2cb4748019471e790a' 
  AND token = '3jmxM+BR5E4JrB2TYRMpBMhqCSRIVpDZRQ7DGF4W4zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}