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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c09bb7ab77d018f17e292406b4e66f30aa609fc0ba39c7e3b16f868abaddb51' 
  AND token = '9issmn36jAR6IQ0ly0MsDchHllnKWLSrk9FQjYDxNpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}