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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf5f11f33f6c86010f2d3eb7a0b61f7297df58ec3d7bf5ef967f9fa9d7e6889' 
  AND token = 'pErTV5dlcbxpggxJxxskvaS2Dj9E+PLqLU9u0OiwUYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}