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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2324c0b9c0e631a74273c0287c67015fe81a0ea4184cc51208e4708ed03048' 
  AND token = 'Mhjyhi2leHaE8L24ANgAgEhoPA6oJiqhBP9bvUB8qm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}