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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '788482a62d4fbefea77fad11ac3377d2db8a82eb90c9be059aa082545eb777be' 
  AND token = 'Iz+Xejpz+2PiimL704l0uHuLPh/Bi5COPJXxJ6qbfcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}