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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17779a0e53832d42a8d097a382f2c6c2b232fa4150be6829d70689c3e086487c' 
  AND token = 'O8Ocp5+WOo4fMcsGDE26jyvDFk9NlaUH7zaDTKMko1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}