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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76899cb19a6eda576991a48e861a7be6b3391a7e64a8dc89f336f861a4dec3a4' 
  AND token = 'BUo50vL/tOegLwChmMhvp/gJneCvBoLt0KpNL1LjTtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}