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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4f1dc7776080e81497f0d986d00612d69e7776681a9d5eb8fa7efe258aac642' 
  AND token = 'cC6LNfGUDJU6uN73wLQEiRqym8J+v6Ugg7IjBu0UxCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}