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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ea6c9bd5f63c72382d5fa8d589ca2fb0ab0704139c005f5ee5a8a04bd3261d' 
  AND token = 'UieRJ22j9WcEc88kTsxyC8s2f79xqKArRuuORE9uV+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}