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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de439685c0f25b521a91a23c182746d7fd7fe685c4b8fa62fb1c94e8749e2c6' 
  AND token = '2/utloadVaBMxXOM81aPyQm3c2v6O3LQJQ4ZWakgvWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}