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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57cb66a3e355ce7f3b1651a24ebf53056473995e8c632152163b5c356c9b0839' 
  AND token = '6tsDFNbmbvr6iEOuMvPGlUdEQ3ZV49xnsQ4urYZvppU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}