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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f7d85d4e15605c3688f08c958f941ea41a5bb9f078073d089c00771592272d' 
  AND token = 'RKBjJLsp1W7mj9kJKoxC8Xz/d95HabIHtDJ+LggdRIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}