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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02e5effcdfa212b0b217f282094bb7ed9a296298374f807ff1c55855a008d16a' 
  AND token = '2H0sN6ARYgdl0Y2Smrp+mrk831qeoo6XQzsC8/XNflk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}