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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9621e5ef1c1f0849c8a9843e4bb0b06870d1f42edfc285d36febc165e1009791' 
  AND token = '1iJRZpX8K6ekbKhpeGneJ8DQFsYJjg0PjaTCeiFJDKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}