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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5cec8591ee4e765c51d3c1c2c0234a556cf6488c799b58cdaf9c7f01024d594' 
  AND token = 'mEaPlUDUlbnouP7nBJOngULyRkUh9RIa6kXVkvTg2rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}