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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5580895387f907b85fce6b8aa0b52a369dd7f811c57e798be5c694cdca88c13' 
  AND token = 'hdK0t2KH5Guj3VUD/7lVsM8I/SmLkjHVTdlAqez3U8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}