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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afbf3f2d6a2e29ada8a793ded7513f3328890b52c493980094cc81e0a032bdf5' 
  AND token = 'DgNjZb7NFx38B3GYz9sOQQvVjpMfPP4fHr0RoS9n83Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}