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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b020dc995712fdda5f207c9c5970f13012091a8e1da4863bb3744f288e11e068' 
  AND token = 'N2/Ewv/3qKwR2cZ1443XusMFQ43MAaSssITS/J8CWug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}