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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5514b752039c88e16ac8cde627db1d5a4d69c0f7fb0bdbfabad34aa55a3a21b2' 
  AND token = '+Fh1oYn4/XwpdavV84iRArOMtnO29lPpEUf4jZOZjeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}