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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378bbf0fa890c9872ec1470e1cf43b529c0b1bba3e61ff944b0bc3dc4b65844d' 
  AND token = 'wvRvdZzcQsB+bMfHfWHl9DgQZDLlYWRvNxiMaeCWAh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}