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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd183e26425632dc08a4b88f4de4fe767a19cb952c7924d242f100b940cda5c' 
  AND token = 'ZTpblIeTB1n+NgkxToZ0ByCfOudA4RjUItU7Lfz1lXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}