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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f2400e920d8ab3b24fbe15ebe4728ff00f946d9ff42d2f0eda3ba274930448' 
  AND token = 'YcZ06WdAPnTBO3uIsbKBCgBtZ/Dk/nynAwacV5EPVvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}