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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125ef59813fa9aa06bca05d0bc50d477a8b5b34f0147904ea41a910aacf4db3f' 
  AND token = 'kudvPj/2GAZEcRxTJO0g4uKXHDnHXwygmfPUGni/LmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}