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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3686d3c3eec671ef5fb19f106e77fb70dc6e4de9b93f033f640a6d6f495e0a6' 
  AND token = '4ACV1YcPI6SrQuh+WhwgV2rL8IvaYvqttLdmEQDu5Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}