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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25fda49e506ea342b080e4eb81caf8a6363166d892e654f517e65ba04625908' 
  AND token = '2345VpALrH9Ssy56Bvf7rlChQLa8PnfT36iUkOAW3fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}