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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e59b14aee5ac0e8ed27d87a897a6a5d5bc327490c71559a7d3a2c2101ae923' 
  AND token = 'igr/T3Lcpjd+vwtCBwDPOsJOpwEtliXrGAH9kVkByuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}