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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eda644f6bbbb3170cd44049198abd9bb5ffc8e655bca24bf43a8b39642f3cf3' 
  AND token = 'UHJRU9WI6/2k/0CAeRMXFCJKnS+BhlZ2Zb4PbzdLxQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}