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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c54de49e6f7d7d097740b9d6499317105e373004b9c293b75e12f707904c5c6' 
  AND token = '/X3RYcBCncmlF7o/jJ470fPPmnXp4SIjtzWSCEkPZnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}