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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f7ce8a1a15afcc2ef52a3de830ff65708d29c8612e1e20b2cb4b27e90faa818' 
  AND token = '1/hi6Id+Zy6S0nm/hqIGAPWBn4Fx6eo/SmL6Br0KB70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}