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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a1d6c7b81db24206d507921fedf3eeee60c9a1a2fe0c9fce22100c3448d1614' 
  AND token = 'CdMYIPcP2ZKMoj0F0x5GDwteMLw58KoDdnQUWchGBKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}