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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100d29bd12abe11cb9ef256778ce9bb7ac49fc3c48f0ba637496207bcb21828b' 
  AND token = 'lB4lFugeoe3W5NdUUDMLHOpvhOE34AQafQcJO7tvrqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}