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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ee4752f8872b17c089298a148b58307e86f70d54e89ca9377ad6db2d9ff6418' 
  AND token = 'BnO4Jspqaf4wDvu9fZeA7vO6NUuotdOmtU5EOp+LyBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}