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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146a0a1d3962e5c156129292b9530460cd77af567467372119e65e476079361d' 
  AND token = 'qHITmI8QpPyodHxeOdXy+IZ4YKzrn54G1FgUFOwZ+vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}