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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425d0689b1566a4268d3bb522323609f99c55a7ba8819dc193a38450f1571766' 
  AND token = 'TM2TFTHw81Qbz3sgD1AN7VG2nRDjdMDuh4TKy8chhnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}