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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9378d8f1a5676eb915b2a8f047608aeefbfb37cb7c2993c6c6e4a7f705049532' 
  AND token = '1PkvWl4EhqA77HWCtc3jQy6aPyrRW5cRaTHQ5oOw05c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}