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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60c7d865700f128ba2fec93527c403479dad8e5b5ebd4ae272d8ce6b09b88edf' 
  AND token = 'F3VFd6d2jMDzJxZx+NVjtBP5Jq/y8MCbECjQrZfC8e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}