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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cedf50f60e3435ca1d2bcf8a303d88de458e8ef6b054f79f348953554c5890de' 
  AND token = 'iUi/3XS/y+CPncOqjLpe/rD20jCoyXAkbMxIUaVMRB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}