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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '333f3cbc3213529749e0234aad980ae6e7c07d04b53dc63453e2b7c3344465c0' 
  AND token = 'E7aLZI+V/xlRO4utSTlg/nvXF2MUqQkXWsFBrdsMPcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}