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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a6ac7e141aca4e51041f99c5046786d9b82f25c0d20371dd23c4e6438cb7ef3' 
  AND token = 'cdE7IIptDLEj/0m8Hf7h0S37A9hpP7QQX5t5GigFRyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}