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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2a60b316ec6b79a6742e7398c39f0db11e2c01f4f24af6a46f3fc0551d6880' 
  AND token = '6H+OkLLwn1QdiBvMt2dOcZkwiEU1vT6K6/5hV+eHUBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}