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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd445db8ded24f26b3b00323d4397ec626b733a272d3f205236ed5a1176c590e9' 
  AND token = 'jc0bWfMuvMe1h7kqKxEcmEaDwlq6SX4N+C7XZc0iT5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}