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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758ef59fe29d318abab54523df38c19b9c4b852e7d6c3e4890ebac35e59ae438' 
  AND token = 'J2v0LdN1fn5MFEmJlAQEIGMNl1s0EwLBnmeSE5qiEZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}