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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462d0069dcbd3f2f62404f9799e40028c58d854cc8acbad01719e6195e52f5ee' 
  AND token = 'Ymr4hI04Tyk/AP1EZ+jLLjaD/GdgiGYS90z4bRABSnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}