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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '127cabf017cf71a769e3653a265259a4a5b8aec140ccfe27b900823144984dc6' 
  AND token = 'CuvtRXBWcE/y8Q226R2GcYSSFCvbdlaSV62VGBDUnuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}