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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1bc6db0ac73ff194c0ef4b20b4d2a67c61db386c1fa5bd611e74084e9c78d6' 
  AND token = 'PuMCkZOHTXdEo0x6FCnIJFKJdrbIJpG5OxaBZETKDZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}