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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48dd25c290942e2d4097c6086e2911a406647fcc63ce3bf4eb7b0e5bb5a0cb29' 
  AND token = 'YMfcppXYpHr2tOgCufCvqDdevSPXY8K2iLDRasJY970=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}